Researchers create DNA-based computer

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Israeli scientists have made a breakthrough in DNA computing, according to a report in Nature magazine. The system, designed by Ehud Shapiro and colleagues at the Weizmann Institute, uses DNA to carry out any calculation and requires little human intervention. Until now, DNA processors have needed intensive tending and have been limited to specific problems. The system emulates a Turing machine, which is one of the fundamental concepts in computing. Such a machine examines data step by step, making decisions on what to do next based on that data. In theory, any Turing machine can do any computing problem. In nature, DNA molecules work in a very similar way, unzipping and recombining according to information coded into sequences of chemicals. The Weizmann system works by encoding input data and software into double-stranded DNA molecules, and mixing them with two enzymes. One enzyme breaks down the input data DNA into snippets of varying length, according to the patterns in it. The other recombines these snippets, based on their patterns and those of the software DNA. This process continues down the input strand until it's finished, at which point an output molecule is created that encodes the final state of the system. Because this system represents a Turing machine, it can be used for a very wide range of problems. Although DNA processing is slow at the level of individual molecules -- typically between 500 and 1000 bits per second, or many millions of times slower than current silicon processors -- it is intrinsically massively parallel. Shapiro and his co-workers estimate that they could run a trillion processes simultaneously in a wineglass, carrying out a billion operations a second while using under a nanowatt. Although this invention is a major advance in DNA computation, it's still far from being useful. By silicon standards, the process has a high error rate and is hard to adapt to complex problems. However, Nature reports, the major potential may lie in intelligent systems that operate within cells, detecting or fixing problems or delivering precisely targeted drugs. See Chips Central for the latest headlines on processors and semiconductors. To find out more about the computers and hardware that these chips are being used in, see ZDNet's Hardware News Section. Have your say instantly, and see what others have said. Click on the TalkBack button and go to the Chips Central forum Let the Chips Central editor know what you think by email. And read other letters.

Talkback

good job. be good do good.

via Facebook 28 December, 2005 07:57
Reply

i hate anyone who creates some thing to replicate human DNA. so you can go screw your self and save human kind.

via Facebook 4 January, 2006 17:17
Reply

I think you guys should have a site that you can make dna on the computer and it will show what it looks like.

via Facebook 4 March, 2006 14:31
Reply

Aw jeez. Yet again, a profusion of idiotic comments.

First off - who said it was human DNA, idiot?

Second off - there's plenty of places on the web to see what DNA looks like - try this, for instance:

http://www.dnalc.org/home.html

As it is, does it mean nothing to you guys that someone has produced a Turing machine at the molecular level? Think about it - a Turing machine can be built to simulate any other system in existence - it's simply a matter of complexity. This is a fantastic step forwards for science - I can only applaud the efforts of this team in pushing the boundaries of the unknown back a little bit further.

via Facebook 6 March, 2006 12:59
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